Potassium Bicarbonate Pure n USP Grade Manufacturers

Anmol Chemicals is the pioneer manufacturers of Potassium Bicarbonate, Pharmaceutical Excipients Food & Flavor chemicals in India. We offer Halal and Kosher Potassium Bicarbonate made in an ISO9001, ISO22000 (FSSC22000) cGMP and GLP certified facility. Our group has several manufacturing facilities spread across the world, supported by toll manufacturers and representatives in UAE, Europe, Africa, USA, China and has several associated manufacturing facilities spread across India. All the Information on Physics, Chemistry, Applications, Uses and Technology on Manufacture of Potassium Bicarbonate is in these pages.

The units in the group have one or more of the certifications like FDA GMP, ISO 9001, ISO 22000, HACCP, REACH, Kosher & Halal and DMF support is available.

Potassium Bicarbonate USP Manufacturers

Potassium Bicarbonate USP grade
KHCO3 100.12
Carbonic acid, monopotassium salt.
Monopotassium carbonate [CAS Number 298-14-6].

Potassium Bicarbonate contains not less than 99.5 percent and not more than 101.5 percent of KHCO3, calculated on the dried basis.

Identification: A solution (1 in 10) responds to the tests for Potassium and for Bicarbonate.
Loss on drying: Dry it over silica gel for 4 hours: it loses not more than 0.3% of its weight.
Normal carbonate: Grind 3.0 g of Potassium Bicarbonate with 25 mL of alcohol and 5 mL of water in a porcelain mortar. Add 3 drops of phenolphthalein TS, and titrate slowly with barium chloride solution, prepared by dissolving 12.216 g of barium chloride in 300 mL of water and diluting with alcohol to obtain 1000 mL of solution, until the suspension becomes colorless. Continue the grinding for 2 minutes, and if the color turns pink, continue the titration with the barium chloride solution to a colorless end-point. Repeat the grinding for 2 minutes and the addition of the barium chloride solution, if necessary, until the suspension is colorless after 2 minutes of grinding. Each mL of the barium chloride solution is equivalent to 6.911 mg of K2CO3: not more than 2.5% is found.
Heavy metals: To 2 g add 5 mL of water and 8 mL of 3 N hydrochloric acid, heat to boiling, and maintain that temperature for 1 minute. Add 1 drop of phenolphthalein TS and sufficient 6 N ammonium hydroxide, drop wise, to give the solution a faint pink color. Cool, add 2 mL of 1 N acetic acid, and then dilute with water to 25 mL: the limit is 0.001%.
Assay: Dissolve about 4 g of Potassium Bicarbonate, accurately weighed, in 100 mL of water, add methyl red TS, and titrate with 1 N hydrochloric acid VS. Add the acid slowly, with constant stirring, until the solution becomes faintly pink. Heat the solution to boiling, cool, and continue the titration until the pink color no longer fades after boiling. Each mL of 1 N hydrochloric acid is equivalent to 100.1 mg of KHCO3.

For Original Monographs of Potassium Bicarbonate please check with the web-pages of the Pharmacopoeia.

Anmol Chemicals
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